Cilocab®

Cilnidipine
Cilocab®

Prescribing Details



Description

Cilocab® is a preparation of Cilnidipine which is a calcium channel blocker. Cilnidipine is lhe calcium antagoniat accompanied wilh L-lype and N-typo calcium channol blocking function. Cilnidipino can act on the N-lype calcium channel lhal existing aympalhelic nerve end besides acting on L-type calcium channel that similar to most of the calcium
antagonists. It inhibits cellular influx of calcium, thus causing vasodilatation. It has greater selectivity for vascular smooth muscle.


Uses

No Data


Indications

Cilocab® is indicated for the treatment of hypertension and hypertensive associated vascular disorders.


Dosage and administration

The recommended adult oral dose of Cilocab® is 5 mg to 10 mg once daily. If needed, the dosage can be increased up to 20 mg.


Use in pregnancy & lactation

Pregnancy: There are no adequate studies of cilnidipine in pregnant women to inform whether there is a drug associated risk in pregnancy. However, caution should be exercised during cilnidipine use in pregnancy.

Lactation: It is not known whether cilnidipine is distributed in human breast milk or not However, caution should be exercised during cilnidipine use in lactation.


Geriatric use
No Data

Precautions

Hypotension, poor cardiac reserve, heart failure. Sudden withdrawal may exacerbale angina. Discontinue in patients who experience iachemic pain following administration.


Side effects
The moat common side effects of cilnidipine are fatigue, ankle swelling, sleepinesa, flushing, hypotension, headache, nausea, dizziness, palpitations, odoma and abdominal pain.

Contraindications

Cilnidipine is conlraindicated in patients with known hypersensitivity to cilnidipine or any other components of this product.


Drug interactions

Cilnidipine can inleracl with aldesleukin, quinidine, phenyloin, rifarnpicin, erythromycin, other anti-hypertensive drugs and anti-psychotic drugs.


Overdose
Overdose of cilnidipine may cause excessive reduction in blood pressure. If reduction in blood pressure is remarkable, appropriate measures such as lifting lower extremities, fluid therapy and administration of vasopressors should be taken.

Preparation

No Data


Pharmaceutical precautions

Store in a cool (below 30° C) and dry place protected from light Keep away from the reach of children.


Presentation

Cilocab® 5 Tablet: Each coated tablet contains Cilnidipine INN 5 mg.
Cilocab® 10 Tablet: Each coated tablet contains Cilnidipine INN 10 mg.


Package quantities

Cilocab® 5 Tablet: Carton of 30 tablets in blister pack.
Cilocab® 10 Tablet: Carton of 30 tablets in blister pack.